Every week a woman in my office asks me some version of the same question. Her mother has dementia. She is fifty-two, she is miserable, and she wants to know whether hormone therapy will protect her brain or ruin it. For twenty years the answer has been that dementia is a risk of hormone therapy. This month we got the most interesting piece of evidence in a long time. What They Found A Stanford group published an autopsy study in Neurology on August 12. They pulled 258 women

A new patient in her early fifties came to see me a few months ago, already six months into estrogen and progesterone and frustrated. The hot flashes were gone. The sleep was better. But she described herself as flat. She was lifting three days a week and getting nothing back for it. Her drive was gone, at work and at home. She told me she felt like a competent, tired stranger doing an impression of herself. She had a thick chart. Thyroid, iron, B12, vitamin D, a full metabol

A man in his late thirties sat in my office last month, complaining of being tired all day, flat in his mood, thicker around the middle than he used to be, and losing interest in things he used to want. He assumed it was work, or age, or that he simply needed to try harder. His total testosterone came back at 310. Technically normal. Fifty years ago, that number in a man his age would have raised eyebrows across the room. I have been having a version of that conversation more

Why many women are being told to stop hormones, and what modern evidence actually shows For many women, hormone therapy has felt confusing, or even frightening ever since large studies from more than 20 years ago raised concerns about its safety. Recently, several of my own patients told me they were advised during routine gynecologic visits to stop hormone therapy immediately due to fears of stroke, heart attack, blood clots, or cancer. That understandably created anxiety. T

For millions of women, hormone replacement therapy (HRT) was once a key part of vitality. But for more than two decades, fear has overshadowed its benefits, until now. November 10, 2025, marks a historic milestone in women’s health: the day the FDA officially removed the black box warning on hormone replacement therapy. This decision, now being referred to as “Menopause Liberation Day,” signals a new era of science-based empowerment for women navigating midlife and beyond. A

When most people think about hormones and aging, testosterone, estrogen, and maybe DHEA come to mind. But there’s another hormone that quietly sits at the top of the cascade, influencing nearly everything else: pregnenolone. Sometimes called the “mother hormone,” pregnenolone is the building block from which many other hormones are made — including progesterone, DHEA, estrogen, testosterone, and cortisol. Like most hormones, pregnenolone levels are high in youth and decline s

I’ve always focused on prevention, vitality, and optimizing health at every age. Today, I’m excited to announce that I’m now offering Hormone Replacement Therapy (HRT) — for both women and men — as part of my commitment to supporting your health span, not just your lifespan. Why Hormones Matter Hormones are powerful messengers that regulate nearly every system in the body — from energy levels and mood to metabolism, muscle strength, brain function, and sexual health. As we ag